Normothermic Regional Perfusion (NRP) is an in situ organ-recovery technique that reestablishes oxygenated blood flow to thoraco/abdominal organs after circulatory determination of death. By restoring physiologic perfusion before organ procurement, NRP helps preserve organ viability, improve transplant outcomes, and expand donor utilization.
NRP may be complemented by machine perfusion, which maintains organs outside the body after recovery using specialized perfusion devices. Together, in situ and machine perfusion strategies extend preservation time, enhance assessment capabilities, and increase transplant suitability.