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Normothermic Regional Perfusion (NRP) Services for Donor Care

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Advanced In-Situ Organ Recovery Through NRP

Normothermic Regional Perfusion (NRP) is an advanced donor care approach that restores circulation to donor organs in situ prior to recovery, helping reduce warm ischemic injury and improve transplant suitability. Our team supports both in-situ NRP and complementary machine perfusion workflows, delivering individualized circuit configurations, advanced device integration, and structured donor management support across neonatal, pediatric, adolescent, and adult donor populations.

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What Is Normothermic Regional Perfusion (NRP)?

Normothermic Regional Perfusion (NRP) is an in situ organ-recovery technique that reestablishes oxygenated blood flow to thoraco/abdominal organs after circulatory determination of death. By restoring physiologic perfusion before organ procurement, NRP helps preserve organ viability, improve transplant outcomes, and expand donor utilization.

NRP may be complemented by machine perfusion, which maintains organs outside the body after recovery using specialized perfusion devices. Together, in situ and machine perfusion strategies extend preservation time, enhance assessment capabilities, and increase transplant suitability.

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Delivering Advanced In-Situ Organ Recovery Through NRP

Our Donor Care team assists with comprehensive NRP services to maximize organ recovery, improve organ placement outcomes, and support Organ Procurement Organizations (OPOs) at every stage of the NRP process.

We offer individualized NRP circuits for neonatal, pediatric, adolescent, and adult cases, ensuring that each donor scenario receives equipment configuration and clinical expertise aligned with the specific physiologic profile.

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What Our NRP Services Include

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Full White Glove NRP Service

Our Total Organ Recovery Solutions program supports complete operational support for both TA-NRP (Thoracoabdominal NRP) and A-NRP (Abdominal NRP) procedures. This structured model ensures that all required equipment, personnel, and clinical resources are available at the designated recovery location.

Our support includes:

  • 24/7 availability of the NRP team for immediate deployment
  • All required cannulas and NRP hardware devices
  • Complete NRP circuit components, disposables, and reservoir supplies
  • Point-of-care (POC) laboratory testing
  • Simulation-based education and dry-run preparation for program readiness
  • Cross-training and operational familiarity with multiple OCS device platforms

This comprehensive approach minimizes logistical gaps, improves case consistency, and supports safe, compliant implementation across diverse donor recovery environments.

Specialized NRP Circuitry

Unlike programs that rely on a single adult circuit for all donor types, we provide population-specific NRP circuitry to enhance safety, optimize flow dynamics, and support improved organ preservation across diverse donor populations.

End‑to‑End NRP Support

Our team partners directly with OPOs and hospital recovery teams to deliver structured NRP implementation, including:

  • On-site perfusion expertise during NRP cases
  • Customized circuit configuration and setup
  • Point-of-care testing and biomedical equipment oversight
  • Real-time physiologic monitoring and rapid clinical response

NRP Program Development & Proctoring

 We provide NRP precepting and proctoring services to support new program launches, cannulation training, and early-stage implementation. Our model emphasizes education, regulatory alignment, surgical-scope boundaries, and long-term competency development.

Additional Machine Perfusion Services Available

We provide comprehensive perfusion services using advanced device platforms that maintain organ viability outside the body. These systems deliver continuous, warm, oxygenated perfusion, enhanced organ assessment, and greater transplant flexibility. Our team is trained and experienced in supporting workflows across multiple device manufacturers, ensuring seamless integration with OPO and transplant center operational requirements.

Why Implement NRP?

Improved Organ Utilization and Recovery

NRP restores circulation to donor organs before procurement, reducing warm ischemic time and increasing transplant suitability. Partner programs report measurable improvements in organ utilization metrics following NRP-supported implementation.

High National Case Experience

Our team has participated in over 2,000 NRP cases nationwide, bringing extensive case exposure, operational insight, and protocol familiarity to each partner program.

Increased Placement Confidence

Clinical and administrative stakeholders consistently report improved predictability, recovery consistency, and placement confidence when structured NRP processes are integrated into donor management workflows.

Frequently Asked Questions

What is normothermic regional perfusion (NRP)?

Normothermic regional perfusion (NRP) is an advanced donor support technique that restores regional circulation after circulatory death, helping preserve organ viability for transplantation.

What types of programs can benefit from NRP support?

Perfusion Solution Inc. supports organ procurement organizations and transplant centers seeking advanced donor management and organ recovery solutions.

Does Perfusion Solution Inc. provide clinical support for NRP cases?

Yes. Perfusion Solution Inc. assists with specialized clinical support for NRP cases based on program structure, operational needs, and recovery workflows.

What does the NRP service process look like from setup to recovery?

The NRP service process includes early coordination, site preparation, circuit configuration, and perfusion initiation. Perfusion Solution Inc. manages physiologic monitoring, supports donor recovery, and provides post-case documentation and review.

What is the difference between TA-NRP and A-NRP?

TA-NRP (thoracoabdominal NRP) restores circulation to both thoracic and abdominal organs, while A-NRP (abdominal NRP) focuses on abdominal organs only. The approach depends on the recovery plan and organs targeted.

How is NRP different from machine perfusion?

NRP restores circulation inside the body before organ recovery, while machine perfusion preserves organs outside the body after procurement using specialized device platforms. Many programs implement both strategies to optimize preservation, assessment, and placement outcomes.

Do you offer proctoring for new NRP programs?

Yes. Perfusion Solution Inc. provides structured NRP precepting and proctoring to support safe program launches, clinical competency development, and workflow integration.

Strengthen Your NRP Program with Expert Support

Improve donor organ viability, enhance operational coordination, and deliver consistent NRP performance with help from Perfusion Solution Inc.

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